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Understanding Polynucleotides

What is Salmon Sperm Polyribonucleotide (PDRN) Therapy?

Salmon sperm PDRN therapy is a skin rejuvenation treatment that uses polynucleotides—naturally derived from salmon sperm DNA—to improve the appearance, hydration, and elasticity of the skin. This treatment has gained popularity due to its regenerative, anti-inflammatory, and anti-aging properties.

Backed by clinical studies and now widely used in aesthetic medicine, PDRN injections have become a go-to for patients looking to refresh dull, aging, or damaged skin without undergoing more invasive procedures.

What Sets Us Apart

How Does It Work?

Once injected into the skin, the polynucleotides from salmon sperm stimulate cellular repair and regeneration. These molecules activate fibroblasts, the cells responsible for collagen production and tissue repair.

By encouraging natural healing, these injections help:

Restore skin elasticity and firmness
Improve hydration and texture
Reduce fine lines and wrinkles
Brighten the complexion

The treatment is typically administered through a series of small injections directly into targeted areas of the face or neck.

Skin Before Treatment

Skin may appear dry, dull, tired, or aged. Common concerns include fine lines, uneven tone, and loss of elasticity. This treatment is often sought by individuals experiencing visible signs of aging or skin damage due to sun exposure, stress, or environmental factors.

Subcutaneous Fat

Subcutaneous fat is the soft layer of fat located just beneath the skin. This is the type of fat you can pinch between your fingers—and it's the most common kind targeted with fat dissolving injections.

Even if you eat clean and exercise regularly, genetics, hormones, and aging can make it hard to eliminate this fat through lifestyle changes alone. Common problem areas include:

Lower belly and FUPA
Love handles
Inner thighs
Upper arms
Chin and jawline

Fat dissolving treatments at Juanderful Aesthetics specifically target this layer of fat to help you reduce bulges and sculpt your shape.

During Treatment

A series of small injections are administered into the treatment area (usually the face or neck) using a very fine needle. The procedure typically lasts 30–45 minutes. A topical numbing cream is applied beforehand to minimize discomfort.

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Immediate After Treatment

Mild redness, swelling, or small bumps (like mosquito bites) may appear at the injection sites. These usually subside within a few hours to a couple of days. Most clients are able to resume normal activities right after the procedure.

Recovery

Healing is generally quick. Any minor swelling or redness typically resolves in 24–72 hours. Proper hydration, sun protection, and avoiding harsh products are recommended during the recovery period. Full integration of the active ingredients takes place over several days.