✨ PRP for Hair Loss: Why You Must Reduce Scalp Inflammation Before Treatment
- Kevin Micheal Daus, M.D.
- Nov 24
- 3 min read
Written by:Jacqueline Boatwright-Daus, BS, MBA, Ed.S., IAT Certified Trichologist, , Founder of Juanderful Aesthetics
⭐ What Is PRP for Hair Loss?
Platelet-Rich Plasma (PRP) is a regenerative hair restoration treatment that uses the healing properties of your own blood to stimulate new growth. A small amount of blood is drawn, spun in a centrifuge, and separated so the platelets become highly concentrated. These activated platelets are rich in natural growth factors that:
repair weakened follicles
increase blood flow to the scalp
strengthen the hair growth cycle
support thicker, healthier regrowth
PRP is one of the most advanced non-surgical treatments for thinning hair, especially for androgenetic alopecia, postpartum shedding, stress-related hair loss, and early stages of scarring alopecias.
But for PRP to work well, the scalp environment must be healthy—and that means inflammation must be under control before treatment begins.
🔥 Why Inflammation Must Be Controlled Before PRP
🔥 1. Inflammation Blocks Follicles From Responding
When the scalp is inflamed, the follicles enter a “defense mode.” Inflamed follicles have:
reduced oxygen
weakened blood flow
disrupted hair cycles
This makes the follicles far less able to respond to the growth signals delivered by PRP.
🔥 2. Inflammatory Cytokines Break Down PRP Growth Factors
PRP contains powerful regenerative proteins like VEGF, PDGF, IGF-1, and EGF. However, inflamed tissue releases destructive cytokines such as IL-6 and TNF-α.
These inflammatory chemicals neutralize or damage the very growth factors PRP is trying to deliver—dramatically reducing treatment effectiveness.
🔥 3. Inflammation Reduces Circulation
Healthy microcirculation is essential for PRP to spread through the tissue and reach the follicles. But inflammation causes swelling, congestion, and poor oxygen flow.
Without strong circulation, the benefits of PRP cannot reach the areas that need repair.
🔥 4. PRP Can Worsen an Active Flare
Injecting PRP into a “hot” scalp—such as during active CCCA, FFA, or LPP—can actually increase inflammation.This may lead to:
burning or tenderness
increased shedding
accelerated fibrosis
faster progression of scarring alopecia
This is why inflammation must be controlled before PRP is started.
🔥 5. Inflammation Leads to Fibrosis, Which Blocks PRP Penetration
Chronic inflammation causes the scalp to develop fibrosis—a thickening of the tissue caused by excess collagen.Fibrosis:
tightens the scalp
compresses the follicles
restricts nutrient absorption
Severe fibrosis prevents PRP from reaching the stem-cell niche needed for regrowth.
🔥 6. PRP Requires a Stable, Regenerative Environment
PRP communicates directly with stem cells in the dermal papilla and outer root sheath. But inflammation forces these cells into a defensive, survival-based state.
For PRP to work, the scalp must be:
calm
oxygenated
balanced
free of immune flares
A cool, stable scalp is the perfect environment for hair regeneration.
⭐ The Bottom Line
PRP is a growth treatment, but inflammation destroys follicles — hair cannot rebuild while the scalp is inflamed. Once inflammation is controlled (especially in conditions like CCCA, FFA, and LPP), PRP becomes more effective, reliable, and long‑lasting. Because PRP can calm mild inflammation but worsen severe inflammation, our clinic determines when and who is ready for PRP — not the patient — ensuring it helps, not harms.
📍 CALL TO ACTION
If you’re ready to restore your hair the Juanderful way with PRP, peptides, advanced trichology treatments, and expert scalp analysis, schedule your consultation today.
📍 Juanderful Aesthetics3006 Clairmont Road, Suite 112Brookhaven, GA 30329📞 678-369-0346
Stay youthful, stay Juanderful!